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Journal: bioRxiv

Article Title: Solution biophysics identifies lipid nanoparticle non-sphericity, polydispersity, and dependence on internal ordering for efficacious mRNA delivery

doi: 10.1101/2024.12.19.629496

Figure Lengend Snippet:

Article Snippet: Samples were injected undiluted in triplicates on an Eclipse TM field flow fractionation (FFF) instrument using a 350 µm fixed-height short channel with dilution control module and a 10 kDa regenerated cellulose membrane (Wyatt Technology, LLC.), connected to a 1260 Infinity II HPLC system with a G1310B isocratic pump and a G1329B autosampler (Agilent Technologies, Inc.).

Techniques: Field Flow Fractionation, Multi-Angle Light Scattering